DSIP is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from rabbit cerebral venous blood during electrically-induced slow-wave sleep, and subsequently studied for its modulatory effects on sleep architecture, stress response, and neuroendocrine regulation.
In research models, DSIP has demonstrated the ability to normalize sleep patterns, reduce stress-induced corticotropin release, modulate LH and GH secretion, and exhibit antioxidant and antimutagenic properties in cellular assays. Its capacity to cross the blood-brain barrier and interact with multiple neuroendocrine axes — including HPA, GH, and gonadotropin systems — makes DSIP a valuable research tool for investigations into sleep biology, stress physiology, pain modulation, and neuroprotection.
Specifications:
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: −20°C
For Research Use Only.







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