Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH), incorporating a [Nle4, D-Phe7] substitution and a cyclic lactam bridge that confer resistance to enzymatic degradation. It is a frequent subject of laboratory research and is supplied as a lyophilized powder for research use only.
In published in vitro and preclinical research, Melanotan 2 has been studied in connection with non-selective agonist activity at the melanocortin receptor subtypes MC1R, MC3R, MC4R, and MC5R. These studies are conducted in cell-culture and animal research models. The findings derive from laboratory research and do not describe or imply any effect, benefit, or use in humans or animals.
Published literature has examined Melanotan 2 across a range of cell-culture and animal research models relating to melanocortin-receptor pharmacology. Its broad, non-selective receptor engagement is studied as a pan-agonist reference tool, in comparison with more selective melanocortin research compounds such as Melanotan 1 and PT-141, allowing receptor-subtype contributions to be examined. These reports reflect controlled laboratory conditions only and do not translate to dosing, treatment, or applications in any other context.
For further reading, see published research on Melanotan 2 on PubMed.
Product Specifications
| CAS Number | 121062-08-6 |
| PubChem CID | 92432 |
| Molecular Formula | C₅₀H₆₉N₁₅O₉ |
| Molecular Weight | ~1,024.2 g/mol |
| Amino Acid Count | 7 (cyclic) |
| Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
| Synonyms | MT-2, MT-II |
| Purity | ≥99% by HPLC | COA available |
| Physical Form | Lyophilized powder |
| Storage Conditions | Store at −20°C; protect from light and moisture |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease. Not for human or animal consumption.













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