GHK-Cu

GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine complexed with Cu²⁺) found in human plasma, saliva, and urine, that has been studied extensively for its remarkable breadth of biological activity — particularly its ability to activate a gene expression program associated with tissue regeneration, wound repair, anti-inflammatory signaling, and antioxidant defense.

Through modulation of TGF-β, SMAD, and matrix metalloproteinase (MMP) pathways, GHK-Cu drives fibroblast proliferation, collagen and elastin synthesis, glycosaminoglycan production, and angiogenesis in dermal and connective tissue research models, while simultaneously reducing oxidative damage and inflammatory cytokine expression at the transcriptional level.

Genomic studies have revealed that GHK-Cu modulates the expression of over 4,000 human genes — including those governing DNA repair, ubiquitin/proteasome function, and mitochondrial energetics — establishing it as one of the most transcriptionally active research peptides in skin biology, wound healing, and anti-aging investigation.

Specifications:

• Purity: ≥99% (HPLC verified)
• Form: Lyophilized powder
• Storage: −20°C

For Research Use Only.