TB-500 is a synthetic form of thymosin beta-4 (TΞ²4), a naturally occurring 43-amino acid polypeptide expressed in mammalian cells. It is a frequent subject of laboratory research and is supplied as a lyophilized powder for research use only.
In published in vitro and preclinical research, TB-500 has been studied in connection with G-actin binding and the regulation of monomeric and filamentous actin equilibrium, and with the integrin-linked kinase (ILK), Akt, and NF-κB signaling pathways. These studies are conducted in cell-culture and animal research models. The findings derive from laboratory research and do not describe or imply any effect, benefit, or use in humans or animals.
Published literature has examined TB-500 across a range of cell-culture and animal research models relating to cytoskeletal organization and cell-migration biology. These reports reflect controlled laboratory conditions only and do not translate to dosing, treatment, or applications in any other context. Its mechanism is studied alongside related research compounds such as GHK-Cu and BPC-157.
For further reading, see published research on TB-500 / thymosin beta-4 on PubMed.
Product Specifications
| CAS Number | 77591-33-4 |
| PubChem CID | 16132341 |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | ~4,963 g/mol |
| Amino Acid Count | 43 |
| Purity | ≥99% by HPLC | COA available |
| Physical Form | Lyophilized powder |
| Storage Conditions | Store at −20°C; protect from light and moisture |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease. Not for human or animal consumption.











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