Thymosin Alpha-1 (Tα1; thymalfasin) is a 28-amino acid acetylated peptide derived from prothymosin alpha, originally isolated from thymic tissue. It is a frequent subject of laboratory research and is supplied as a lyophilized powder for research use only.
In published in vitro and preclinical research, Thymosin Alpha-1 has been studied in connection with agonist activity at Toll-like receptor 2 (TLR2) and Toll-like receptor 9 (TLR9) on myeloid and dendritic cells, and with associated dendritic-cell and T-cell maturation signaling. These studies are conducted in cell-culture and animal research models. The findings derive from laboratory research and do not describe or imply any effect, benefit, or use in humans or animals.
Published literature has examined Thymosin Alpha-1 across a range of cell-culture and animal research models relating to TLR-mediated signaling and thymic-peptide biology. These reports reflect controlled laboratory conditions only and do not translate to dosing, treatment, or applications in any other context. Its mechanism is studied alongside related research compounds such as Thymalin, KPV, and VIP.
Thymosin Alpha-1 is supplied as a lyophilized powder requiring reconstitution prior to laboratory use. It reconstitutes well in phosphate-buffered saline (PBS).
For further reading, see published research on Thymosin Alpha-1 on PubMed.
Product Specifications
| CAS Number | 62304-98-7 |
| Molecular Formula | C₁₂₉H₂₁₅N₃₃O₅₅ |
| Molecular Weight | ~3,108 g/mol |
| Amino Acid Count | 28 |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN |
| Synonyms | Thymalfasin, Tα1, TA-1 |
| Purity | ≥99% by HPLC | COA available |
| Physical Form | Lyophilized powder |
| Storage Conditions | Store at −20°C; protect from light and moisture |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease. Not for human or animal consumption.











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