Tesamorelin is a synthetic analog of human GHRH in which the native 44-amino acid sequence is conjugated to a trans-3-hexenoic acid moiety — a modification that confers stability against plasma degradation while preserving full biological activity at pituitary GHRH receptors.
Tesamorelin is the only GHRH analog with FDA approval (for HIV-associated lipodystrophy), and its clinical and preclinical research portfolio is extensive — spanning visceral adiposity reduction, IGF-1 axis modulation, cognitive function in aging, MASH-related hepatic fat reduction, and cardiovascular risk marker improvement.
Research models have demonstrated tesamorelin’s ability to produce robust, sustained GH and IGF-1 elevation through preserved pulsatile mechanisms, reduce trunk fat selectively, and improve lipid profiles — making it a highly characterized compound for GH axis, metabolic, and body composition research.
Specifications:
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: −20°C
For Research Use Only.
Robert H. –
Very happy with this Tesamorelin. COA showed 99.2% purity and it arrived well within the estimated delivery window. AminoForge has quickly become my preferred supplier.