Pinealon

Pinealon (Glu-Asp-Arg) is a synthetic tripeptide bioregulator derived from the pineal gland, developed by Vladimir Khavinson and studied for its ability to penetrate the blood-brain barrier and directly regulate gene expression in neuronal and retinal cells through epigenetic mechanisms — specifically by binding to DNA promoter regions and modulating transcription factor activity associated with neuroprotection, antioxidant defense, and circadian regulation.

Research in aging models has demonstrated Pinealon’s ability to reduce neuronal apoptosis, restore age-diminished neurotransmitter synthesis, upregulate BDNF and NGF expression, attenuate oxidative damage in brain tissue, and improve behavioral performance in cognitive function assays. Its particular affinity for pineal and retinal tissue makes it a specialized research compound for investigations into circadian biology, melatonin pathway regulation, retinal neuroprotection, and age-related neurodegeneration.

Specifications:

• Purity: ≥99% (HPLC verified)
• Form: Lyophilized powder
• Storage: −20°C

For Research Use Only.