Thymosin Alpha-1 (Tα1) is a 28-amino acid acetylated peptide naturally secreted by thymic epithelial cells that functions as a master immunomodulator — coordinating innate and adaptive immune responses through Toll-like receptor (TLR) activation, dendritic cell maturation, T-helper cell differentiation, and NK cell cytotoxic enhancement.
Unlike immunostimulants that broadly amplify immune activity, Tα1 exhibits bidirectional immunoregulatory properties — capable of both upregulating deficient immune responses and attenuating pathological immune hyperactivation, making it a uniquely versatile research tool for immunology studies.
It has been investigated across a broad spectrum of research contexts including viral and bacterial infection resistance, vaccine adjuvancy, autoimmunity modulation, oncology immune support, and COVID-19 immunopathology — with its biological activity in human clinical settings among the most extensively documented of any thymic peptide.
Reconstitute using Phosphate-buffered saline (PBS) instead of Bacteriostatic Water for best results.
Specifications:
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: −20°C
For Research Use Only.
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