MOTS-c is a synthetic 16-amino acid mitochondrial-derived peptide (MDP). Its sequence is encoded within the 12S rRNA gene region of mitochondrial DNA — unusual among peptides, which are typically encoded by nuclear DNA. It is a frequent subject of laboratory research and is supplied as a lyophilized powder for research use only.
In published in vitro and preclinical research, MOTS-c has been studied in connection with the AMP-activated protein kinase (AMPK) signaling pathway and cellular energy-metabolism processes. These studies are conducted in cell-culture and animal research models. The findings derive from laboratory research and do not describe or imply any effect, benefit, or use in humans or animals.
Published literature has examined MOTS-c across a range of cell-culture and animal research models relating to mitochondrial-derived peptide biology and AMPK-linked signaling. These reports reflect controlled laboratory conditions only and do not translate to dosing, treatment, or applications in any other context. Its mechanism is studied alongside related mitochondrial research compounds such as SS-31.
For further reading, see published research on MOTS-c on PubMed.
Product Specifications
| CAS Number | 1627580-64-6 |
| PubChem CID | 146675088 |
| Molecular Formula | C₁₀₁H₁₅₂N₂₈O₂₂S₂ |
| Molecular Weight | ~2,174.6 g/mol |
| Amino Acid Count | 16 |
| Sequence | MRWQEMGYIFYPRKLR |
| Synonyms | Mitochondrial-Derived Peptide (MDP) |
| Purity | ≥99% by HPLC | COA available |
| Physical Form | Lyophilized powder |
| Storage Conditions | Store at −20°C; protect from light and moisture |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease. Not for human or animal consumption.
Dr. Linda M. –
MOTS-C from AminoForge is top notch. Purity confirmed by the COA and reconstitution was flawless. Shipping was fast and packaging completely discreet. Will be a repeat customer.