Peptide Receptor Modulator Research Series — Dual Agonist Investigational Compound.
DIA-39-C20 is a synthetic 39-amino acid dual incretin receptor agonist built on a GIP peptide backbone, engineered with strategic residue substitutions enabling balanced, high-affinity co-engagement of both the GIP receptor (GIPR) and the GLP-1 receptor (GLP-1R). It is a frequent subject of laboratory research and is supplied as a lyophilized powder for research use only.
In published preclinical research, DIA-39-C20 has been studied in connection with combined GIPR/GLP-1R receptor binding and downstream cyclic AMP (cAMP) signaling, with investigations extending to glucose-regulation pathways, insulin-secretion dynamics, glucagon-suppression signaling, gastric-motility modulation, and lipid-metabolism biochemistry. These studies are conducted in cell-culture and animal research models. The findings derive from laboratory research and do not describe or imply any effect, benefit, or use in humans or animals.
Published literature has examined DIA-39-C20 across a range of cell-culture and animal research models relating to dual incretin receptor co-activation biology. These reports reflect controlled laboratory conditions only and do not translate to any research amount, clinical use, or application outside these controlled conditions. Its receptor mechanism is studied alongside related research compounds such as Single Regulator, Triple Regulator, and Amylin Analog.
For further reading, see published research on dual incretin receptor agonists on PubMed.
Product Specifications
| CAS Number | 2023788-19-2 |
| PubChem CID | 156588324 |
| Molecular Formula | C₂₂₅H₃₄₈N₄₈O₆₈ |
| Molecular Weight | 4,813.45 g/mol |
| Amino Acid Count | 39 |
| Amino Acid Sequence | H-Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys(γ-Glu-(2×AEEA)-eicosanedioyl)-Ile-Ala-Gln-Lys-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ |
| Synonyms | Tirzepatide (research analog), GIPR/GLP-1R dual-agonist research class, LY3298176 |
| Purity | ≥99% by HPLC | COA available |
| Physical Form | Lyophilized powder |
| Storage Conditions | Store at −20°C; protect from light and moisture |
For Research Use Only. Not for use in diagnostic, medical, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not intended to diagnose, manage, mitigate, or prevent any illness or medical condition. Not for human or animal consumption.
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