Peptide Receptor Modulator Research Series — Dual Agonist Investigational Compound.
DIA-39-C20 is a synthetic 39-amino acid dual incretin receptor agonist built on a GIP peptide backbone, engineered with strategic residue substitutions enabling balanced, high-affinity co-engagement of both the GIP receptor (GIPR) and GLP-1 receptor (GLP-1R). Its simultaneous activation of both incretin receptors produces distinct downstream signaling profiles compared to selective GLP-1R monoagonists, making it a primary research tool for investigating dual incretin pathway mechanisms, receptor co-activation kinetics, and comparative incretin biology.
Preclinical and clinical research models have examined DIA-39-C20 across metabolic research applications including glucose regulation, insulin secretion dynamics, glucagon suppression, gastric motility, lipid metabolism, hepatic fat accumulation, and cardiovascular parameters.
Product Specifications
| CAS Number | 2023788-19-2 |
| Molecular Formula | C₂₂₅H₃₄₈N₄₈O₆₈ |
| Molecular Weight | 4,813.45 g/mol |
| Amino Acid Count | 39 |
| Amino Acid Sequence | H-Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys(γ-Glu-(2×AEEA)-eicosanedioyl)-Ile-Ala-Gln-Lys-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ |
| Purity | ≥99% by HPLC | COA available |
| Physical Form | Lyophilized powder |
| Storage Conditions | Store at −20°C; protect from light and moisture |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not intended to diagnose, treat, cure, mitigate, or prevent any disease. Not for human or animal consumption.
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